The authors concluded that chamomile extract produced a clinically meaningful reduction comparable to conventional anxiolytic drug therapy. More comparative effectiveness trials between chamomile and conventional drugs are still needed to identify optimal use of chamomile for GAD. Adverse events were reported in almost 12% of subjects, though none were identified as serious events. Statistically significant and clinically meaningful reductions in secondary outcome ratings of anxiety and wellbeing also occurred. The primary outcome evaluated was the frequency of clinical response and change in GAD-7 symptom scores by week 8.ĥ8% of the participants met criteria for the clinical response and participants also experienced significant improvement over time on the GAD-7 rating.
In one study, subjects with moderate to severe GAD received open-label treatment with pharmaceutical-grade chamomile extract 1,500 mg/day for up to 8 weeks. No adverse effects were reported in the chamomile group.Ĭhamomile can also be used for anxiety. In one study of 60 elderly people (single-blind RCT), comparing placebo capsule to 200 MG twice daily of a standardized chamomile extract, the chamomile group had significantly improved sleep quality as compared to the control group. Apigenin binds to specific receptors in your brain that may decrease anxiety and initiate sleep. Its calming effects may be attributed to an antioxidant called apigenin, which is found in abundance in chamomile tea.
Chamomile for Anxiousness and SleepĪs noted above, Chamomile is commonly regarded as a mild tranquilizer or sleep inducer. The use of chamomile has been described in medical texts from ancient Egypt, Greece, and Rome. This review will focus on the use of German Chamomile. For medicinal purposes, German Chamomile is generally thought to be more potent. It is included in the pharmacopoeia of 26 countries. German Chamomile (Matricaria recutita) is one of the most widely used herbal remedies in the world.
The two most common species of chamomile are German Chamomile (Marticaria recutita) and Roman Chamomile (Chamaemelum nobile). It may be helpful for knee osteoarthritis, ulcerative colitis, premenstrual syndrome, and gastrointestinal disorders. The herb smells somewhat like an apple, which may explain its name, rooted from the Greek word khamaimēlon or "earth apple."Ĭhamomile is also utilized for its antioxidant, antimicrobial, anti-inflammatory, antidiarrheal, angiogenesis, and anticarcinogenic activities. It is thought that chamomile may increase brain neurotransmitter activity (serotonin, dopamine, and noradrenaline) and thereby have positive effects on mood and anxiety. Chamomile is widely recognized as a mild tranquilizer and sleep-inducer.
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